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Hemophilia A and B are clotting disorders involving a deficiency of a specific clotting factor (A: Factor VIII, B: Factor IX) needed for appropriate homeostasis. They are caused by a sex-linked recessive genetic mutation. Affected dogs will show inappropriate hemorrhage including bruising, lameness induced by bleeding into joints and body cavity hemorrhage. It can be diagnosed with a slow APTT and demonstrating low levels of the factor involved. Hemophilia A is more common than B and is generally, more severe. Because it is sex-linked recessive, males are more likely to be affected than females but females still act as carriers, so genetic screening is important prior to breeding to prevent this disease.
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Hepatic encephalopathy is a neurologic condition in cats and dogs that is caused by an underlying liver condition. It can cause lethargy, seizures, problems with balance and coordination, and coma. Common causes, methods to diagnose the condition, and its treatment options are explained in this handout.
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Hepatic lipidosis, also known as fatty liver syndrome, is unique to cats and is one of the most common liver diseases seen in cats. Usually a cat with hepatic lipidosis has recently gone through a period of anorexia (little or no eating) for 3 to 4 consecutive days. Diagnosis of hepatic lipidosis is made from blood tests that demonstrate poor liver function and/or from a liver biopsy or fine needle aspirate. Hepatic lipidosis is treatable with aggressive nutritional support until a normal appetite returns. Treating the underlying initial cause of the inappetence is also essential for full recovery.
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This handout explains hepatic microvascular dysplasia, a condition where microscopic blood vessels within the liver are underdeveloped or absent, resulting in decreased blood flow to the liver. As a result, the liver is less capable of dealing with toxins or producing the vital proteins needed for good health. Methods to diagnose the condition and its treatment options are also explained.
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Hepatoid gland tumors are a type of cancer that develop from the sebaceous (sweat) glands of the skin. The most common location for these tumors to develop is the perianal area, and the most common tumor is the perianal adenoma. Perianal adenocarcinomas, and rarely perianal epitheliomas may also occur. These tumors appear as one or more small, round, pink, hairless, slow-growing nodules around the anus, and can sometimes ulcerate and become infected. Malignant tumors can grow much bigger and faster, invade the underlying tissue, and metastasize. Diagnosis may be made by fine needle aspiration, biopsy, or full excision of the tumor. Staging is recommended for adenocarcinomas. Treatment may involve surgical removal along with neutering, cryotherapy, laser ablation, radiotherapy, chemotherapy, and occasionally hormone therapy. The prognosis is good with perianal adenomas, fair to poor with adenocarcinomas, and generally good with epitheliomas.
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Hepatozoonosis in dogs is caused by ingestion of one of two organisms: H. americanum and H. canis. Both parasites are more common in the southern United States. The clinical sign and treatments for dogs with hepatozoonosis differ depending on the parasite species causing the infection. In either case, with appropriate treatment, the prognosis is generally good.
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Canine herpesvirus, or canine herpes, is a systemic, often fatal disease of puppies caused by the canine herpes virus. It may remain latent in tissues after a dog is infected and may be passed on to other dogs, particularly to fetuses developing in the mother's uterus. Clinical signs in puppies include difficulty breathing, nasal discharge, anorexia, soft stools, crying, seizures, and sudden death. Symptoms in adult dogs include coughing and sneezing, miscarriage, lesions on the external genitalia, conjunctivitis, and corneal ulcers. The disease may be prevented by avoiding contact with infected dogs. Pregnant dogs should be isolated to prevent infection.
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Feline viral rhinotracheitis (FVR) is an infectious disease caused by feline herpesvirus type-1. It is a major cause of upper respiratory disease in cats and is the most common cause of conjunctivitis. The typical symptoms of FVR involve the nose, throat, and eyes, and include sneezing, nasal congestion, conjunctivitis, excessive blinking, squinting, and discharges from the eyes and nose that range from clear and watery to thick and purulent (containing yellow/green pus). Treatment consists of supportive care, hydration of the environment, and control of secondary bacterial infections with antibiotics and antibiotic eye medications. An effective vaccine exists and is recommended for all cats.
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The most common cause of hip dislocation is blunt force trauma such as a fall or an automobile injury. Most dogs with a hip dislocation will have severe hind limb lameness and pain and may not be able to put any weight on the affected limb. A diagnostic radiograph will show the direction of dislocation and whether a fracture of any part of the hip joint has occurred. In many cases, it is possible to replace the femoral head in the acetabulum by manipulation under general anesthesia. If the femoral head has been successfully replaced and the correct post-operative treatment has been adhered to, it is unlikely that the hip will dislocate again.
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Hip dysplasia is a deformity of the hip that occurs during growth. The result is laxity of the joint, followed by degenerative joint disease (DJD) or osteoarthritis (OA), which is the body's attempt to stabilize the loose hip joint. Hip dysplasia is a genetic disease that is affected by factors such as diet, environment, exercise, growth rate, muscle mass, and hormones. It is predominantly seen in larger dogs. Treatment depends upon the pet's clinical signs and amount of discomfort the pet is in.